← All comparisons · Cardiovascular event prevention
Which interventions reduce all-cause mortality?
Outcome definition: Death from any cause. Definition is identical across trials.
Every intervention below was measured against the same outcome, so their effects are lined up on one axis. They are not pooled together. Relative effects (risk ratios) are broadly comparable, but the interventions were studied in different populations (see the Population column), so absolute benefit and NNT are not directly comparable across rows.
Effect on all-cause mortality
Each row is a different intervention's pooled effect on the same outcome. Interventions are not pooled together—this is a comparison, not a meta-analysis.
Interventions
| Intervention | Population | RR [95% CI] | Improvement | NNT | Studies | Status |
|---|---|---|---|---|---|---|
| CoQ10 in Chronic Heart Failure (Q-SYMBIO) | Chronic heart failure (HF) | 0.58 [0.35–0.95] | 42% | 14 | 1 | Limited data |
| Statins for secondary prevention | Established cardiovascular disease | 0.82 [0.75–0.91] | 18% | 43 | 4 | Favorable |
| Statins for primary prevention | Cardiovascular disease (primary prevention) | 0.83 [0.73–0.95] | 17% | 183 | 3 | Limited data |
NNT is shown where a baseline risk was available; it reflects each intervention's own study population and follow-up, so NNTs are not comparable between rows with different baseline risk.